Xiaflex is a non-surgical treatment option for Dupuytren’s contracture. This medication is used to break-up or dissolve the Dupuytren’s cords in patients hands. Recovery is quicker than open fasciectomy surgery. Most patients have significant improvement in the flexion contracture, but recurrence of the contracture is common. Many patients need an additional treatment for the hand in 3-5 years. The results are similar to needle aponeurotomy procedures. Complications include pain, bruising, swelling, nerve injury, allergic reaction, skin tears, lymph node swelling, and tendon rupture. Bruising and swelling can be severe in some patients, but this almost always goes away over time.